Getting a meeting
You then need to take a delicate but necessary step to try to get an interview with the employer after sending your speculative application. This next step (if well managed) is seen as a sign of perseverance, motivation and professionalism.
If you don't get a response within ten days, call to check that your mail has arrived . If you get a positive response, say again briefly how keen you are to join the company and try to get an interview.
Please see the advice in the article "Managing reminders", which also applies to speculative applications.